How Probiotics can Help to Fight Cancer
Researchers have discovered that probiotics, which are the "good" bacteria that live in your gut, play a significant role in many diseases including cancer. While probiotics are widely recognized for fighting pathogens in the body and improving gut health, they sometimes help to prevent tumor progression and cancer, according to the latest scientific research.
This is especially timely since cancer diagnosis appears to be on the upswing. According to a Global Burden of Diseases Injuries, and Risk Factors study, 18.7 million people worldwide received a cancer diagnosis in 2010 compared with 23.6 million people in 2019. And cancer is appearing in people younger than age 50 at a dramatic rate around the world, according to The Harvard Gazette. The good news is probiotics are shown to have many anti-cancer effects, including promising results for treatments.
Probiotics and Colon Cancer
It's estimated that almost 700,000 yearly deaths are caused each year by colon cancer. A study published in Oxidative Medicine and Cellular Longevity revealed that harmful changes in the microbiota composition create conditions for tumor growth and intestinal inflammation. The study showed that specific probiotics can treat and even reverse this condition.
A mixture of prebiotics and probiotics was administered to 37 participants with colorectal cancer and 43 colonic polypectomy patients showed that the abundance of two specific probiotics increased, while a food poisoning-linked bacterium decreased in CRC patients. In patients who had polyps removed, Here’s how probiotics can help to fight colon cancer, according to a study published in Oncology Reviews:
- enhancing the host’s immune response
- altering the metabolic activity of the intestinal microflora
- binding and degrading carcinogens
- producing antimutagenic compounds
- altering the physiochemical conditions in the colon
Probiotics and Cervical Cancer
Each year, 13,000 women in the United States are diagnosed with cervical cancer. Many clinical studies have shown that probiotics can help to prevent cervical cancer. A study published in the European Journal of Cancer Prevention found that women who took probiotics had a “twice as high chance of clearance of their HPV-infection-related cytological abnormality as a control group.”
Clinical Nutrition ESPEN reports that “numerous clinical studies have demonstrated the efficacy of probiotics in preventing cervical cancer." Another study published in the European Journal of Cancer Prevention discovered that women who took probiotics had a “twice as high chance of clearance of their HPV-infection-related cytological abnormality as a control group.”
A study in the European Journal of Cancer Prevention found that probiotics were responsible for the following actions:
- normalization of gut microbiota
- decrease of harmful substances produced by intestinal bacteria
- enhancement of NK [natural killer]-cell activity
Probiotics and Breast Cancer
Each year in the United States, approximately 264,000 women are diagnosed with breast cancer, and 42,000 die. A recent study published in Oncology Reviews reported that probiotics demonstrated efficacy with breast cancer in an animal study. There was a significant increase in the survival time among the group who took probiotics compared to that of the controls, which showed that probiotics can promote an effective immune response.
Another study found evidence that diet and probiotics can exert important anti-carcinogenic effects in breast cancer. They found that gut microbiota plays a vital part in the metabolism of chemotherapeutic drugs and in the activity of immunogenic chemotherapies, which can help make them more effective.
Pancreatic Cancer and Probiotics
One of the most lethal cancers is pancreatic cancer. Despite its high mortality rate, probiotics may offer hope for prevention and treatment, according to a study published in the journal, Nutrients. The reason is the proven link between gut microbiota and pancreatic cancer, which has been intensely studied over the past several years. Researchers found that alterations of gut microbiota can affect pancreatic carcinogenesis, and microbes may affect the tumorigenic pathway. It's believed that by supplementing the gut microbiota with probiotics and prebiotics, it may open new healing strategies and therapies for pancreatic cancer patients.”
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